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Full Name and Common Aliases


Frances Arnold is a renowned American biochemist and professor, known for her groundbreaking work in the field of directed evolution.

Birth and Death Dates


Born on January 25, 1956

Nationality and Profession(s)


American biochemist and professor

Early Life and Background


Frances Arnold was born in Washington, D.C., to a family with a strong background in science. Her father, Robert Arnold, was an engineer at NASA's Langley Research Center, while her mother, Jane Arnold, was a mathematics teacher. Growing up, Frances showed a keen interest in chemistry, which eventually led her to pursue a degree in chemical engineering from the Massachusetts Institute of Technology (MIT).

Major Accomplishments


Arnold's most notable contribution is the development of directed evolution, a powerful tool for creating new enzymes and other biological molecules. Her work has been instrumental in advancing our understanding of protein engineering and has far-reaching implications for biotechnology. Some of her key accomplishments include:

Development of directed evolution as a method for improving enzyme activity
Creation of novel enzymes with unprecedented properties
Discovery of new mechanisms for protein folding

Notable Works or Actions


Some of Arnold's notable works include:

"Directed Evolution: A Powerful Tool for Creating New Enzymes" (a seminal paper that outlined the principles and applications of directed evolution)
"The Design of Evolvable Molecules" (a book co-authored with her colleague, George Georgiou)

Impact and Legacy


Frances Arnold's work has had a profound impact on various fields, including biotechnology, pharmaceuticals, and synthetic biology. Her pioneering research has paved the way for the development of novel enzymes, therapeutics, and biofuels. As a result, she has been recognized with numerous awards, including:

Nobel Prize in Chemistry (2018)
* National Medal of Science (2011)

Why They Are Widely Quoted or Remembered


Frances Arnold is widely quoted and remembered for her innovative approach to problem-solving and her tireless advocacy for the importance of basic scientific research. Her work has inspired countless scientists and engineers, who seek to emulate her dedication to advancing our understanding of the natural world. As she once said in an interview: "The beauty of directed evolution is that it allows us to tap into the vast creativity of nature itself."

Quotes by Frances Arnold

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Instead of studying what biology has already made, we have to imagine what biology could make. You can say, 'Oh, I want a cure for cancer,' but that doesn't tell you what evolutionary pathway will take you from here to there. What are the intermediate steps?
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When I started engineering proteins I didn't know how hard it would be.
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What I want to do is encourage women to take on this incredibly exciting and fun challenge to use their brains for the benefit of humanity but through science and technology.
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All my projects are about sustainability, bioremediation, making things in a cleaner fashion.
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Nature's made much more dangerous things than I ever will.
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No human can design a good enzyme, yet we are surrounded by them after 3.5 billion years of work by evolution.
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There's plenty of ordinary Nobel laureates.
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I've done that my whole life - I've taken the way people think and turned it on its head.
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I've been called pushy and aggressive and all the negative words that are rarely applied to men with the same traits. But it doesn't bother me.
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I wanted to develop a career where I could use my engineering background to have a positive effect on society.
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